While expressing support to split Ghosn's posts, he said the "absolute priority" of the next chairman would be to strengthen the alliance, while the chief executive would be responsible for the day-to-day running of the company.
Senard faces the immediate task of soothing relations with Nissan, which is 43.4 percent owned by Renault and the junior partner in the alliance, despite making more sales. "It is our compulsory duty to go forward together".
The Nissan president said what matters now is stabilizing the relationship between the two firms and preparing an environment in which jobs can be done with a sense of security.
The appointments mark a clear end to one of the auto industry's most-feted careers, two decades after Ghosn was dispatched by former Renault CEO Louis Schweitzer to rescue newly acquired Nissan from near bankruptcy - a feat he pulled off in two years.
"Carlos Ghosn just resigned last night", Le Maire said. As Bloomberg points out, both men will need to fix ties with Nissan and strengthen the alliance, which reached the weakest point in its history in the wake of Ghosn's arrest.
Last month, Japanese prosecutors indicted Ghosn and Kelly on charges of underreporting the former chairman's compensation.
Both men deny the deferred pay was illegal or required disclosure, while not contesting the agreements' existence. Ghosn has also denied a separate breach of trust charge over personal investment losses he temporarily transferred to Nissan in 2008.
The announcement came hours after reports that Ghosn had stepped down from both roles.
Senard has been at the helm of French tire company Michelin for nearly seven years.
Renault's board met on Thursday to formally accept Ghosn's resignation and outline his successors.
New Renault chairman Jean-Dominique Senard, left, shakes hands with Renault CEO Thierry Bollore after being appointed following a meeting of the board held at Renault headquarters in Boulogne-Billancourt, outside Paris, France, Thursday.
During his run as head of Renault since 2005, Ghosn was the cornerstone in its alliance with Nissan and Mitsubishi as the three big names carved out a major role for themselves in the industry as a force to be reckoned with. "We are very pleased to be able to open a new chapter in our historic partnership", he added.
Le Maire called Nissan's move a "positive signal" for the alliance. Now is not the time to discuss structural changes, Saikawa reiterated on Thursday.