Cal Fire Captain - John Gaddie - said the town of just 27,000 was "destroyed" by the flames. By nightfall, it had consumed more than 28 square miles and firefighters had no containment, McLean said.
The Reno Fire Department and South Lake Fire Rescue have both sent strike teams to the fire, and the Placer County Sheriff's Office says they are heading that way to help with evacuations.
An evacuation warning was issued for parts of Chico Thursday night as the Camp Fire blazed toward the city of 90,000 people.
He said sheriff's deputies helped patients evacuate.
The Ventura County Fire Department has also ordered evacuation of some communities in the path of the fire, which erupted a few miles from the site of Wednesday night's deadly mass shooting at a Thousand Oaks bar. The message I want to get out is: "If you can evacuate, you need to evacuate".
Christy Dawn Little abandoned her Oak Park home, northeast of Thousand Oaks, around 11 p.m. PT.
Flames from the unchecked, 8,100-hectare Camp Fire, which began early Thursday, were being driven westward by 56 km/h winds, fire officials said.
By Friday morning, a day after the fire broke out at Pulga Road at Camp Creek Road, firefighters said about 80 percent of the town, population 26,000 was lost.
"F-ing Paradise is gone", she said.
Adventist Health Feather River Medical Center and all schools in Paradise Unified School District evacuated due to the blaze.
The extent of people's injuries was not immediately known as officials could not access the risky area, 180 miles northeast of San Francisco.
Social media was flooded with apocalyptic imagery of smoke-filled skies and horizon lines of neon orange.
Four of the hospital's employees were briefly trapped in the basement and rescued by California Highway Patrol officers, Kinney said.
"The wind that was predicted came and just wiped it out".
Vaughan could hear screams and explosions nearby as she and her husband got in their auto and drove away Thursday. Herrera, who lives in Paradise with her 88-year-old husband, Lou Herrera, left a frantic voicemail at around 9:30 a.m. saying they needed to get out.
May said the low humidity and the dryness of trees and brush are among the reasons for the Camp Fire and also pose a potential danger in Berkeley.
Cal Fire said strong winds were moving the fire quickly.
Richardson estimates another 60,000 people will likely have to evacuate because the fire jumped USA 101 early Friday and is pushing toward the coast.
A Red Flag Warning is in place through Friday morning in the Butte County area, and winds are expected to gust at speeds as high as 40 miles per hour overnight, according to the National Weathers Service.