Al-Thawra Hospital, Yemen's biggest, was caught in the attack.
According to a doctor at Al Thawra Hospital many injured have been transferred to other hospitals and "there is a large number of deaths, and we can not count now because the number is large, above the capacity of the hospital".
The Saudi-led coalition backing Yemeni's internationally recognised government has been fighting to defeat the rebels, known as Houthis, since March 2015.
"The scenes coming from Hodeida are horrific".
Horrific images, videos, and witness accounts of the bombing quickly began circulating on social media after airstrikes pounded the vicinity of al-Thawra, Hodeidah's main public hospital.
Colonel Turki Al Malki, Spokesman for the Arab Coalition Forces, yesterday accused the Houthi militias of carrying out mortar attacks, while confirming that the Coalition did not carry out any operations targeted in the vicinity of the area affected.
The same report also quoted rebel-run Al Masirah TV which said the attack killed 52 people and left more than 100 wounded.
But strikes have picked up again around Hodeida since the Saudis last week said that two oil tankers operated by one of the kingdom's companies were attacked in the waters of the Red Sea.
The halt to retaliatory attacks in the Red Sea is aimed at "preserving the Yemeni bloods and in response to the regional and global moves and efforts aiming to bring peace", he noted.
Britain's UN Ambassador Karen Pierce, the current council president, said after the meeting that "there was very strong support" for Griffiths and "we're united in his efforts to get the parties to Geneva".
World Health Organization officials on Friday called on the sides to halt fighting for at least three days for a vaccination effort that aims to prevent another deadly wave of cholera.