It's likely that he will be met with a frosty reception from the Saints faithful, as he returns to St Mary's Stadium for the first time since the move.
Lovren has until the end of the season to try and establish a partnership with Van Dijk, and if he cannot then next summer he could well be replaced by another new addition.
The Holland worldwide is expected to receive a hostile reception at St Mary's due to the events which preceded his eventual move to Anfield earlier this year.
"I don't know exactly but probably it will not be the most friendly", he told reporters at a press conference. I have already took part in some marketing actions of the club and it has always been very nice to feel this affection of the young fans with me.
Klopp will have to think about rotation for this match, with one eye on their Valentine's Day Champions League game against Porto coming up midweek. It was quite a public deal and the numbers, even when they are not 100 percent correct, are OK, so maybe they are really happy. and it was not on objective.
"It is not that I ask 'do you want to play?' You say a few words", Klopp said. We are influenced by circumstance. It will not be a normal game, how can it be? How can it be?
"I can see, in the Premier League, you cannot have the flawless overview of the Bundesliga and, in the Bundesliga, you cannot have the ideal overview of the Premier League".
"It's how football fans are". Will it have influence?
I can not see the Saints suffering relegation.
The England global was shown a straight red after grabbing Tottenham youngster George Marsh by the neck in a furious reaction to a challenge.
'As a former footballer when I saw the other challenge, to be honest, I understand a little bit but it's not to excuse.
"I'm very happy here at Liverpool and I do not see myself out of that club for years to come".
"But it doesn't change my mind about Adam, of course". That's how it is. "Liverpool have a squad with great players and I'm sure our manager has solutions in the group to fill that gap". I was working up in Scotland when he first signed for Dundee United and he was getting more exposure.
Southampton boss Mauricio Pellegrino has said that his side "are in a good situation" to face Liverpool on Sunday afternoon.